2bind

Meet us at the Bio Convention in San Diego - either at the booth, via partnering, or externally, we'd love to connect. Thomas Schubert and Cosimo Kropp are excited to meet already-known and new people! https://lnkd.in/dKrXuHVa

At 2bind, we value the power of ideas. That's why we are committed to safeguarding intellectual property with care and diligence. It's not only about protecting our own work, but also about respecting the creativity of others. For us it’s about respect and collaboration in the scientific community.

At 2bind, we value the power of ideas. That's why we are committed to safeguarding intellectual property with care and diligence. It's not only about protecting our own work, but also about respecting the creativity of others. For us it’s about respect and collaboration in the scientific community.

Recently, I had the pleasure of speaking at the Bio-Incubator in Leuven - a space filled with innovative biotech companies. Connecting with familiar faces and meeting new ones truly made my day, and I'm grateful for the opportunity to share insights with such a vibrant community. During the seminar, we looked into a drug discovery project, exploring the discovery process from establishing biophysical assays to Hit identification and confirmation, and eventually concluding with lead optimization. Titled "The Power of Biophysics," the seminar posed the bold question: What is the power of biophysics? It is the unique ability to deliver a direct readout - a key differentiator compared to most other applications. During the seminar, I was met with clever questions from the audience, such as the effects of protein modification on protein integrity, the impact of compound aggregation on binding results, and the variety of protein constructs out there and the pain to choose the right construct. The importance of clear and actionable data in drug discovery projects is evident. While non-biophysical assays are capable of processing ultra-high throughput campaigns, data ambiguity often hinders understanding of druggability of a target, mode-of-action, and often it remains discussable if there is clear interaction between drug candidates and the protein target at all. As I reflect on our time together, I'm reminded of the power of collaboration and the effectiveness of integrating various assays to approach projects from diverse perspectives. If you're facing similar challenges in your drug discovery projects or seeking clarity in your assay data, I'd love to connect and to discuss perspectives.

It is time for the Swiss Biotech Days! 2bind will be there from April 22-23, so leave us a message - we are always eager to talk science and have a drink or a snack. https://swissbiotechday.ch

You are in need of Epitope Binning, a ternary complex formation study for your PROTACs or other assays? We proudly present our newest aquisition: the BLI Octet RED 384 instrument! Contact us at contact@2bind.com to learn which assays and solutions we can provide!

Behind the scenes - the foundation story of 2bind GmbH and NanoTempers‘ role in it: Everything startet back in 2011. Professor Gernot Längst from the University of Regensburg had a good idea. He approached us. And then we’ve founded the Contract Research Organisation (CRO) 2bind GmbH together with him. Why did we do that? The idea was, to make our new biophysical technology „MicroScale Thermophoresis“ available for everyone. Everyone needs molecular interaction measurements in free solution. Not everyone must own an instrument to do so. There is the need for instruments. There is the need for services. At NanoTemper we fully focus on high quality instruments. So we founded 2bind together with Gernot in 2011: to cover the need for services. To make MicroScale Thermophoresis measurements available - as a service. The idea worked well! We got Thomas Schubert on board. As CEO he shaped and grew 2bind globally. 2016, NanoTemper stepped back, 2bind thrives independently. 2bind is now fully independent since years. It provides a wide range of different biophysical measurement services. Not only from NanoTemper Technologies but also from Dynamic Biosensors and many more. And this is good. I’ve visited them in their new rooms - they’ve just expanded. Great to see so many biophysical instruments. Do you want to read more “behind the scenes” posts? What interests you the most? #biotechnology #entrepreneurship #startup ————————— I am Philipp - founder, CEO & business angel. My bootstrapped company NanoTemper is a global leader for biophysical tools for biotech. Like my content? Click my name + follow + 🔔

Meet us at the BioEurope Spring in Barcelona! There is always time to have a coffee and chat about achievements and how to overcome struggels in research. Just shoot us a meeting request, we'd be happy to connect! https://lnkd.in/eRdjEqv