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Intestinal Absorption: Transport of Water
    * Water Absorption
Most relevant to the function of the large intestine but also occurs in the small intestine.
– Large intestine stores and concentrates fecal material before elimination. – Mainly absorbs water and electrolytes to do so – Also absorbs bacterial byproducts.
  • Three General Steps of Water Absorption:
Step 1:
  • Sodium-potassium pump on the basolateral surface
– Pumps K+ into cell and Na+ out of cell (pump utilizes ATP to move sodium and potassium against their concentration gradients).
  • Na+ passively enters via general sodium ion transporter on the apical surface (possible because of the active transport of sodium out of the cell)
  • Net positive charge in the cell
Step 2:
  • Chloride enters the cell through a general chloride ion transporter on the apical surfacen via facilitated diffusion down the electrical gradient.
  • Higher solute concentration inside the cell relative to the lumen.
Step 3:
  • Water crosses the apical surface via osmosis.

Intestinal Absorption: Transport of Water

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Water Absorption
  • The main function of the large intestine is to store and concentrate fecal material before elimination.
    • It mainly absorbs water and electrolytes to do so, but that it also absorbs bacterial byproducts.
  • Basolateral surface
  • Apical surface
    • Sodium ion transporter (passive)
    • Chloride ion transporter (pasive)
    • Water enters via osmosis