Skip to main content
SpringerLink
Log in

Mesenchymale und neuronale Tumoren

  • Chapter
  • First Online:
Braun-Falco’s Dermatologie, Venerologie und Allergologie

Part of the book series: Springer Reference Medizin ((SRM))

  • 980 Accesses

Zusammenfassung

Mesenchymale und neuronale Tumoren geben sich klinisch häufig nur schwer zu erkennen. Farbe, Lage und Tastbefund der Läsion sind zur differenzialdiagnostischen Abwägung hilfreich. Entsprechend der anatomischen Lokalisation mesenchymaler Strukturen wird zwischen Neoplasien des Bindegewebes und Fettgewebes, der glatten und quer gestreiften Muskulatur, des Knorpelgewebes und Knochengewebes sowie peripheren Nervensystems unterschieden. Für die präzise Einordnung dieser Läsionen ist eine repräsentative Gewebeentnahme mit dermatohistopathologischer Untersuchung häufig unerlässlich. Hierbei haben sich zahlreiche immunhistochemische Marker bewährt. Mit Einführung der Molekularbiologie sind bei einigen Entitäten Fluoreszenz-in-situ-Hybridisierung und Reverse-Transkriptase-Polymerase-Kettenreaktion zusätzlich diagnostisch hilfreich geworden. Darüber hinaus haben bei einigen malignen Neoplasien chromosomale Aberrationen prognostische und therapeutische Relevanz.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 369.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

Bindegewebe

  • Agaimy A, Haller F (2016) CTNNB1 (β-Catenin)-altered neoplasia: a review focusing on soft tissue neoplasms and parenchymal lesions of uncertain histogenesis. Adv Anat Pathol 23:1–12

    Article  PubMed  CAS  Google Scholar 

  • Allen PW, Dymock RB, MacCormac LB (1988) Superficial angiomyxomas with and without epithelial components. Am J Surg Pathol 12:519–530

    Article  PubMed  CAS  Google Scholar 

  • Antal A, Zelger B, Reifenberger J et al (2007) Multiple eruptive myxoid dermatofibromas: report of first case and review of literature. Br J Dermatol 157:382–385

    Article  PubMed  CAS  Google Scholar 

  • Bansal C, Stewart D, Li A et al (2005) Histologic variants of fibrous papule. J Cutan Pathol 32:424–428

    Article  PubMed  Google Scholar 

  • Charli-Joseph Y, Saggini A, Doyle LA et al (2014) DNA copy number changes in tumors within the spectrum of cellular, atypical, and metastasizing fibrous histiocytoma. J Am Acad Dermatol 71:256–263

    Article  PubMed  CAS  Google Scholar 

  • Di Vito A, Scali E, Ferraro G et al (2015) Elastofibroma dorsi: a histochemical and immunohistochemical study. Eur J Histochem 59:2459. https://doi.org/10.4081/ejh.2015.2459

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Doyle LA, Fletcher CD (2013) Metastasizing „benign“ cutaneous fibrous histiocytoma: a clinicopathologic analysis of 16 cases. Am J Surg Pathol 37:484–495

    Article  PubMed  Google Scholar 

  • Doyle LA, Marino-Enriquez A, Fletcher CDM et al (2015) ALK rearrangement and overexpression in epithelioid fibrous histiocytoma. Mod Pathol 28:904–912

    Article  PubMed  CAS  Google Scholar 

  • Erdag G, Qureshi HS, Patterson JW et al (2007) Solitary fibrous tumors of the skin: a clinicopathologic study of 10 cases and review of the literature. J Cutan Pathol 34:844–850

    Article  PubMed  Google Scholar 

  • Folpe AL (2014) Fibrosarcoma: a review and update. Histopathology 64:12–25

    Article  PubMed  Google Scholar 

  • Gawron K, Lazarz-Bartyzel K, Potempa J et al (2016) Gingival fibromatosis: clinical, molecular and therapeutic issues. Orphanet J Rare Dis 11:9. https://doi.org/10.1186/s13023-016-0395-1

    Article  PubMed  PubMed Central  Google Scholar 

  • Gengler C, Guillou L (2006) Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology 48:63–74

    Article  PubMed  CAS  Google Scholar 

  • Gray MH, Smoller BR, McNutt NS et al (1990) Giant dermal dendrocytoma of the face: a distinct clinicopathologic entity. Arch Dermatol 126:689–690

    Article  PubMed  CAS  Google Scholar 

  • Griewank KG, Schilling B, Murali R et al (2014) TERT promotor mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas. Mod Pathol 27:502–508

    Article  PubMed  CAS  Google Scholar 

  • Grynspan D, Meir K, Senger C et al (2007) Cutaneous changes in fibrous hamartoma of infancy. J Cutan Pathol 34:39–43

    Article  PubMed  CAS  Google Scholar 

  • Luzar B, Calonje E (2009) Superficial acral fibromyxoma: clinicopathological study of 14 cases with emphasis on a cellular variant. Histopathology 54:375–377

    Article  PubMed  Google Scholar 

  • Mansoor A, White CR Jr (2003) Myxofibrosarcoma presenting in the skin: clinicopathological features and differential diagnosis with cutaneous myxoid neoplasms. Am J Dermatopathol 25:281–286

    Article  PubMed  Google Scholar 

  • Martignetti JA, Tian L, Li D et al (2013) Mutations in PDGFRB cause autosomal-dominant infantile myofibromatosis. Am J Hum Genet 92:1001–1007

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Martin L, Piette F, Blanc P et al (2005) Clinical variants of the preprotuberant stage of dermatofibrosarcoma protuberans. Br J Dermatol 153:932–936

    Article  PubMed  CAS  Google Scholar 

  • Mentzel T, Scharer L, Kazakov DV et al (2007) Myxoid dermatofibrosarcoma protuberans: clinicopathologic, immunohistochemical, and molecular analysis of eight cases. Am J Dermatopathol 29:443–448

    Article  PubMed  Google Scholar 

  • Mentzel T, Wiesner T, Cerroni L et al (2013) Malignant dermatofibroma: clinicopathological, immunohistochemical, and molecular analysis of seven cases. Mod Pathol 26:256–267

    Article  PubMed  Google Scholar 

  • Miller K, Goodlad JR, Brenn T (2012) Pleomorphic dermal sarcoma: adverse histologic features predict aggressive behavior and allow distinction from atypical fibroxanthoma. Am J Surg Pathol 36:1317–1326

    Article  PubMed  Google Scholar 

  • Nickoloff BJ, Wood GS, Chu M et al (1990) Disseminated dermal dendrocytomas. A new cutaneous fibrohistiocytic proliferative disorder? Am J Surg Pathol 14:867–871

    Article  PubMed  CAS  Google Scholar 

  • Nishi SP, Brey NV, Sanchez RL (2006) Dermal nodular fasciitis: three case reports of the head and neck and literature review. J Cutan Pathol 33:378–382

    Article  PubMed  Google Scholar 

  • Saab ST, McClain CM, Coffin CM (2014) Fibrous hamartoma of infancy: a clinicopathologic analysis of 60 cases. Am J Surg Pathol 38:394–401

    Article  PubMed  Google Scholar 

  • Shah KN, Anderson E, Junkins-Hopkins J et al (2007) Medallion-like dermal dendrocyte hamartoma. Pediatr Dermatol 24:632–636

    Article  PubMed  Google Scholar 

  • Spaun E, Zelger B (2009) Dermatofibroma with intracytoplasmic eosinophilic globules: an unusual phenomenon. J Cutan Pathol 36:796–798

    Article  PubMed  Google Scholar 

  • Tap WD, Wainberg ZA, Anthony SP et al (2015) Structure-guided blockade of CSF1R kinase in tenosynovial giant-cell tumor. N Engl J Med 373:428–437

    Article  PubMed  CAS  Google Scholar 

  • Tardio JC, Pinedo F, Aramburu JA et al (2016) Pleomorphic dermal sarcoma: a more aggressive neoplasm than previously estimated. J Cutan Pathol 43:101–112

    Article  PubMed  Google Scholar 

  • Thway K, Fisher C (2015) Angiomatoid fibrous histiocytoma: the current status of pathology and genetics. Arch Pathol Lab Med 139:674–682

    Article  PubMed  CAS  Google Scholar 

  • Thway K, Jones RL, Noujaim J et al (2016a) Epithelioid sarcoma: diagnostic features and genetics. Adv Anat Pathol 23:41–49

    Article  PubMed  CAS  Google Scholar 

  • Thway K, Ng W, Noujaim J et al (2016b) The current status of solitary fibrous tumor: diagnostic features, variants, and genetics. Int J Surg Pathol 24:281–292

    Article  PubMed  CAS  Google Scholar 

  • Vivero M, Doyle LA, Fletcher CD et al (2014) GRIA2 is novel diagnostic marker for solitary fibrous tumour identified through gene expression profiling. Histopathology 65:71–80

    Article  PubMed  Google Scholar 

  • Warren RB, Verbov JL, Ashworth M (2007) Precalcaneal congenital fibrolipomatous hamartoma. Pediatr Dermatol 24:74–75

    Article  PubMed  Google Scholar 

  • Weinstein JM, Drolet BA, Esterly NB et al (2003) Congenital dermatofibrosarcoma protuberans: variability in presentation. Arch Dermatol 139:207–211

    Article  PubMed  Google Scholar 

  • Wilk M, Schmoeckel C, Kaiser HW et al (1995) Cutaneous angiomyxoma: a benign neoplasm distinct from cutaneous focal mucinosis. J Am Acad Dermatol 33:352–355

    Article  PubMed  CAS  Google Scholar 

  • Wilk M, Zelger BG, Nilles M et al (2004) The value of immunohistochemistry in atypical cutaneous fibrous histiocytoma. Am J Dermatopathol 26:367–371

    Article  PubMed  Google Scholar 

  • Wilk M, Zelger BG, Debiec-Rychter M et al (2015) Angiomatöses fibröses Histiozytom – Fallserie mit Schwerpunkt auf der späten fibrotischen Variante. J Dtsch Dermatol Ges 13:441–449

    PubMed  Google Scholar 

  • Wilk M, Zelger BG, Zelger B (2015) Fibrosarcomatous dermatofibrosarcoma protuberans with myoid nodules. J Cutan Pathol 42:782–785

    Article  PubMed  Google Scholar 

  • Wilk M, Zelger BG, Zelger B (2016) Hemosiderotic fibrolipomatous tumor. Am J Dermatopathol 38:714–716

    Article  PubMed  Google Scholar 

  • Wilson Jones E, Cerio R, Smith NP (1989) Epithelioid cell histiocytoma: a new entity. Br J Dermatol 120:185–195

    Article  Google Scholar 

  • Yu G, Wang Y, Wang G et al (2015) Fibrous hamartoma of infancy: a clinical pathological analysis of seventeen cases. Int J Clin Exp Pathol 8:3374–3377

    PubMed  PubMed Central  CAS  Google Scholar 

  • Zelger B, Soyer HP (2000) Between Scylla and Charybdis: mythology in dermatopathology. Dermatopathol Pract Concept 6:348–355

    Google Scholar 

  • Zelger BG, Zelger B (2001) Skin lesions of fibrocytic and fibrohistiocytic differentiation: a new concept and classification. Curr Top Pathol 94:103–140

    Article  PubMed  CAS  Google Scholar 

  • Zelger BW, Steiner H, Kutzner H (1996) Clear cell dermatofibroma. Case report of an unusual fibrohistiocytic lesion. Am J Surg Pathol 20:483–491

    Article  PubMed  CAS  Google Scholar 

  • Zelger B, Zelger BG, Burgdorf WH (2004) Dermatofibroma – a critical evaluation. Int J Surg Pathol 12:333–344

    Article  PubMed  Google Scholar 

Fettgewebe

  • Billings SD, Folpe AL (2007) Diagnostically challenging spindle cell lipomas: a report of 34 „low-fat“ and „fat-free“ variants. Am J Dermatopathol 29:437–442

    Article  PubMed  Google Scholar 

  • Dei Tos AP, Mentzel T, Fletcher CD (1998) Primary liposarcoma of the skin: a rare neoplasm with unusual high grade features. Am J Dermatopathol 20:332–338

    Article  PubMed  CAS  Google Scholar 

  • Evans HL (1979) Liposarcoma. A study of 55 cases with reassessment of its classification. Am J Surg Pathol 3:507–523

    Article  PubMed  CAS  Google Scholar 

  • Leffell DJ, Braverman IM (1986) Familial multiple lipomatosis. Report of a case and review of the literature. J Am Acad Dermatol 15:275–279

    Article  PubMed  CAS  Google Scholar 

  • Nishio J (2011) Contributions of cytogenetics and molecular cytogenetics to the diagnosis of adipocytic tumors. J Biomed Biotechnol 2011:524067. Epub 11 Jan 2011. Review

    Article  PubMed  PubMed Central  Google Scholar 

  • Wilk M, Zelger BG, Zelger B (2013) Adenolipoma – eccrine and apocrine variants with evidence for a hamartomatous process. Am J Dermatopathol 35:138–141

    Article  PubMed  Google Scholar 

Glatter Muskel

  • Alam NA, Barclay E, Rowan AJ et al (2005) Clinical features of multiple cutaneous and uterine leiomyomatosis: an underdiagnosed tumor syndrome. Arch Dermatol 141:199–206

    PubMed  Google Scholar 

  • Badeloe S, van Geel M, van Steensel MA et al (2006) Diffuse and segmental variants of cutaneous leiomyomatosis: novel mutations in the fumarate hydratase gene and review of the literature. Exp Dermatol 15:735–741

    Article  PubMed  CAS  Google Scholar 

  • Hachisuga T, Hashimoto H, Enjoji M (1984) Angioleiomyoma. A clinicopathologic reappraisal of 562 cases. Cancer 54:126–130

    Article  PubMed  CAS  Google Scholar 

  • Holst VA, Junkins-Hopkins JM, Elenitsas R (2002) Cutaneous smooth muscle neoplasms: clinical features, histologic findings, and treatment options. J Am Acad Dermatol 46:477–490

    Article  PubMed  Google Scholar 

  • Kienast A, Maerker J, Hoeger PH (2007) Myokymia as a presenting sign of congenital smooth muscle hamartoma. Pediatr Dermatol 24:628–631

    Article  PubMed  CAS  Google Scholar 

  • Kraft S, Fletcher CDM (2011) Atypical intradermal smooth muscle neoplasms: clinicopathologic analysis of 84 cases and a reappraisal of cutaneous „leiomyosarcoma“. Am J Surg Pathol 35:599–607

    Article  PubMed  Google Scholar 

  • Winchester DS, Hocker TL, Roenigk RK (2015) Skin metastases of leiomyosarcoma (LMS): a retrospective review of 21 cases. J Am Acad Dermatol 72:910–912

    Article  PubMed  Google Scholar 

Quergestreifte Muskulatur

  • Alaggio R, Zhang L, Sung YS et al (2016) A molecular study of pediatric spindle and sclerosing rhabdomyosarcoma: identification of novel and recurrent VGLL2-related fusions in infantile cases. Am J Surg Pathol 40:224–235

    PubMed  PubMed Central  Google Scholar 

  • Chang Y, Dehner LP, Egbert B (1990) Primary cutaneous rhabdomyosarcoma. Am J Surg Pathol 14:977–982

    Article  PubMed  CAS  Google Scholar 

  • Farris PE, Manning S, Vuitch F (1994) Rhabdomyomatous mesenchymal hamartoma. Am J Dermatopathol 16:73–74

    Article  PubMed  CAS  Google Scholar 

  • Lee KA, Won H-S, Shim J-Y et al (2013) Molecular genetic, cardiac and neurodevelopmental findings in cases of prenatally diagnosed rhabdomyoma associated with tuberous sclerosis complex. Ultrasound Obstet Gynecol 41:306–311

    Article  PubMed  CAS  Google Scholar 

  • Missiaglia E, Williamson D, Chisholm J et al (2012) PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification. J Clin Oncol 30:1670–1677

    Article  PubMed  Google Scholar 

  • Rosenberg AS, Kirk J, Morgan MB (2002) Rhabdomyomatous mesenchymal hamartoma: an unusual dermal entity with a report of two cases and a review of the literature. J Cutan Pathol 29:238–243

    Article  PubMed  Google Scholar 

  • Szuhai K, de Jong D, Leung WY et al (2014) Transactivating mutation of the MYOD1 gene is a frequent event in adult spindle cell rhabdomyosarcoma. J Pathol 232:300–307

    Article  PubMed  CAS  Google Scholar 

  • Walther C, Mayrhofer M, Nilsson J et al (2016) Genetic heterogeneity in rhabdomyosarcoma revealed by SNP array analysis. Genes Chromosomes Cancer 55:3–15

    Article  PubMed  CAS  Google Scholar 

Knorpel und Knochen

  • Conlin PA, Jimenez-Quintero LP, Rapini RP (2002) Osteomas of the skin revisited: a clinicopathologic review of 74 cases. Am J Dermatopathol 24:479–483

    Article  PubMed  Google Scholar 

  • Conner JR, Hornick JL (2013) SATB2 is a novel marker of osteoblastic differentiation in bone and soft tissue tumours. Histopathology 63:36–49

    Article  PubMed  Google Scholar 

  • Kobos JW, Yu GH, Varadarajan S et al (1995) Primary cutaneous osteosarcoma. Am J Dermatopathol 17:53–57

    Article  PubMed  CAS  Google Scholar 

  • Larsen S, Davis DM, Comfere NI et al (2010) Osteosarcoma of the skin. Int J Dermatol 49:532–540

    Article  PubMed  Google Scholar 

  • Sakai JN, Abe KT, Formigli LM et al (2011) Cytogenetic findings in 14 benign cartilaginous neoplasms. Cancer Genet 204:180–186

    Article  CAS  Google Scholar 

  • Toida M, Sugiyama T, Kato Y (2003) Cartilaginous choristoma of the tongue. J Oral Maxillofac Surg 61:393–396

    Article  PubMed  Google Scholar 

Peripheres Nervensystem

  • Dehner LP (1993) Primitive neuroectodermal tumor and Ewing’s sarcoma. Am J Surg Pathol 17:1–13

    Article  PubMed  CAS  Google Scholar 

  • Gupta SG, Wang LC, Penas PF et al (2006) Sentinel lymph node biopsy for evaluation and treatment of patients with Merkel cell carcinoma: the Dana-Farber experience and meta-analysis of the literature. Arch Dermatol 142:685–690

    Article  PubMed  Google Scholar 

  • Heath M, Jaimes N, Lemos B et al (2008) Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features. J Am Acad Dermatol 58:375–381

    Article  PubMed  PubMed Central  Google Scholar 

  • Klapman MH, Chun D (1991) Cutaneous and subcutaneous neuroblastoma in children and adults: case reports and population study. J Am Acad Dermatol 24:1025–1027

    Article  PubMed  CAS  Google Scholar 

  • Lebbe C, Becker JC, Grob JJ et al (2015) Diagnosis and treatment of Merkel cell carcinoma. European consensus-based interdisciplinary guideline. Eur J Cancer 51:2396–2403

    Article  PubMed  Google Scholar 

  • Lewis KG, Weinstock MA, Weaver AL et al (2006) Adjuvant local irradiation for Merkel cell carcinoma. Arch Dermatol 142:693–700

    PubMed  Google Scholar 

  • Louis CU, Shohet JM (2015) Neuroblastoma: molecular pathogenesis and therapy. Annu Rev Med 66:49–63

    Article  PubMed  CAS  Google Scholar 

  • Mott RT, Smoller BR, Morgan MB (2004) Merkel cell carcinoma: a clinicopathologic study with prognostic implications. J Cutan Pathol 31:217–223

    Article  PubMed  Google Scholar 

  • Requena L, Sangüeza OP (1995) Benign neoplasms with neural differentiation: a review. Am J Dermatopathol 17:75–96

    Article  PubMed  CAS  Google Scholar 

  • Tashiro A, Imafuku S, Furue M (2008) Traumatic neuroma of the lower lip with intraepithelial nerve fibers. J Cutan Pathol 35:320–323

    Article  PubMed  Google Scholar 

Verschiedene Tumoren

  • Boyd AS, Rapini RP (1994) Cutaneous collision tumors. An analysis of 69 cases and review of the literature. Am J Dermatopathol 16:253–257

    Article  PubMed  CAS  Google Scholar 

  • Bridge JA (2014) The role of cytogenetics and molecular diagnostics in the diagnosis of soft-tissue tumors. Mod Pathol 27:S80–S97

    Article  PubMed  Google Scholar 

  • Costigan DC, Doyle LA (2016) Advances in the clinicopathologic and molecular classification of cutaneous mesenchymal neoplasms. Histopathology 68:776–795

    Article  PubMed  Google Scholar 

  • Eloy-Garcia Carrasco C, Benguigui Benadiva J, Martinez Garcia S et al (2006) Atypical primary carcinoid tumour of the skin. J Cutan Pathol 33(Suppl 2):32–34

    Article  PubMed  Google Scholar 

  • Fletcher CDM (2014) Recently characterized soft tissue tumors that bring biologic insight. Mod Pathol 27:S98–S112

    Article  PubMed  Google Scholar 

  • Fletcher CDM, Bridge JA, Hogendoorn P et al (Hrsg) (2013) World Health Organization classification of tumours of soft tissue and bone. IARC Press, Lyon

    Google Scholar 

  • Hornick JL (2014) Novel uses of immunohistochemistry in the diagnosis and classification of soft tissue tumors. Mod Pathol 27:S47–S63

    Article  PubMed  CAS  Google Scholar 

  • Tran TA, Muller S, Chaudahri PJ et al (2005) Cutaneous carcinosarcoma: adnexal vs. epidermal types define high- and low-risk tumors. Results of a meta-analysis. J Cutan Pathol 32:2–11

    Article  PubMed  Google Scholar 

Erstbeschreiber

  • Abrikossoff A (1926) Über Myome, ausgehend von der quergestreiften, willkürlichen Muskulatur. Virchows Arch Pathol Anat 260:215–233

    Article  Google Scholar 

  • Albright F, Burnett CH, Smith PH et al (1942) Pseudo-hypoparathyroidism: an example of „Seabright-Bantam syndrome“. Endocrinology 30:922–932

    CAS  Google Scholar 

  • Bart RS, Andrade R, Kopf AW et al (1968) Acquired digital fibrokeratomas. Arch Dermatol 97:120–129

    Article  PubMed  CAS  Google Scholar 

  • Bednar P (1957) Storiform neurofibromas of the skin, pigmented and non-pigmented. Cancer 10:368–376

    Article  PubMed  CAS  Google Scholar 

  • Chassaignac CME (1852) Cancer de la gaine des tendons. Gaz Hosp Civ Mil 47:185

    Google Scholar 

  • Chung EB, Enzinger FM (1978) Chondroma of soft parts. Cancer 41:1414–1424

    Article  PubMed  CAS  Google Scholar 

  • Chung EB, Enzinger FM (1979) Fibroma of tendon sheath. Cancer 44:1945–1954

    Article  PubMed  CAS  Google Scholar 

  • Darier J, Ferrand M (1924) Dermato-fibromes progressifs et récidivants ou fibro-sarcomes de la peau. Ann Dermatol Syphiligr 5:545–562

    Google Scholar 

  • Enzinger FM (1965) Clear cell sarcoma of tendons and aponeuroses: an analysis of 21 cases. Cancer 18:1163–1174

    Article  PubMed  CAS  Google Scholar 

  • Enzinger FM (1970) Epithelioid sarcoma. A sarcoma simulating a granuloma or a carcinoma. Cancer 26:1029–1041

    Article  PubMed  CAS  Google Scholar 

  • Enzinger FM (1979) Angiomatoid malignant fibrous histiocytoma: a distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm. Cancer 44:2147–2157

    Article  PubMed  CAS  Google Scholar 

  • Enzinger FM, Harvey DA (1975) Spindle cell lipoma. Cancer 36:1852–1859

    Article  PubMed  CAS  Google Scholar 

  • Enzinger FM, Shiraki M (1972) Extraskeletal myxoid chondrosarcoma. An analysis of 34 cases. Hum Pathol 3:421–435

    Article  PubMed  CAS  Google Scholar 

  • Evans HL (1995) Desmoplastic fibroblastoma. A report of seven cases. Am J Surg Pathol 19:1077–1081

    Article  PubMed  CAS  Google Scholar 

  • Ewing J (1921) Diffuse endothelioma of bone. Proc N Y Pathol Soc 21:17–24

    Google Scholar 

  • Feraudy S de, Fletcher CDM (2012) Fibroblastic connective tissue nevus: a rare cutaneous lesion analyzed in a series of 25 cases. Am J Surg Pathol 36:1509-1515

    Google Scholar 

  • Fetsch JF, Laskin WB, Miettinen M (2001) Superficial acral fibromyxoma: a clinicopathologic and immunohistochemical analysis of 37 cases of a distinctive soft tissue tumor with a predilection for the fingers and toes. Hum Pathol 32:704–714

    Article  PubMed  CAS  Google Scholar 

  • Fitzpatrick TB, Gilchrest BA (1977) Dimple sign to differentiate benign from malignant pigmented cutaneous lesions. N Engl J Med 296:1518

    Article  PubMed  CAS  Google Scholar 

  • Frank A (1908) Ein Fall von angeborenen Fibromen am Finger nebst Beiträgen zur Kasuistik von Fingertumoren. Wien Klin Rundsch 22:659

    Google Scholar 

  • Gery L (1914) Discussions. Bull Mem Soc Anat (Paris) 89:111

    Google Scholar 

  • Graham JH, Sanders JB, Johnson WC et al (1965) Fibrous papule of the nose: a clinicopathological study. J Invest Dermatol 45:194–203

    Article  PubMed  CAS  Google Scholar 

  • Harkin JC, Reed RJ (1969) Tumors of the peripheral nervous system. In: Atlas of tumor pathology series 2, fascicle 3. Armed Forces Institute of Pathology, Washington, DC, S 60–64

    Google Scholar 

  • Headington JT (1976) Tumors of the hair follicle: a review. Am J Pathol 85:479–514

    PubMed  PubMed Central  CAS  Google Scholar 

  • Helwig EB (1963) Case 6-atypical fiboxanthoma. In: 18th annual tumor seminar of the San Antonio Society of Pathologist. Tex State J Med 59:664–667

    Google Scholar 

  • Howard WR, Helwig EB (1960) Angiolipoma. Arch Dermatol 82:924–931

    Article  PubMed  CAS  Google Scholar 

  • Hügel H (1991) Die plaqueförmige dermale Fibromatose. Hautarzt 42:223–226

    PubMed  Google Scholar 

  • Jarvi O, Saxen E (1961) Elastofibroma dorse. Acta Pathol Microbiol Scand 51(Suppl 144):83–84

    Google Scholar 

  • Kamino H, Lee JY, Berke A (1989) Pleomorphic fibroma of the skin: a benign neoplasm with cytologic atypia. A clinicopathologic study of eight cases. Am J Surg Pathol 13:107–113

    Article  PubMed  CAS  Google Scholar 

  • Keasbey LE (1953) Juvenile aponeurotic fibroma (calcifying fibroma): a distinctive tumor arising in the palms and soles of young children. Cancer 6:338–346

    Article  PubMed  CAS  Google Scholar 

  • Klemperer P, Rabin CB (1931) Primary neoplasms of the pleura. A report of five cases. Arch Pathol 11:385–412

    Google Scholar 

  • Kloepfer HW, Krafchuk J, Derbes V et al (1958) Hereditary multiple leiomyoma of the skin. Am J Hum Genet 10:48–52

    PubMed  PubMed Central  CAS  Google Scholar 

  • Konwaler BE, Keasbey L, Kaplan L (1955) Subcutaneous pseudosarcomatous fibromatosis (fasciitis). Am J Clin Pathol 25:241–252

    Article  PubMed  CAS  Google Scholar 

  • Larralde de Luna M, Riuz León J, Cabrera HN (1990) Pápules podálicas en el recién nacido. Med Cutan Ibero Lat Am 18:9–12

    PubMed  CAS  Google Scholar 

  • Launonen V, Vierimaa O, Kiuru M et al (2001) Inherited susceptibility to uterine leiomyomas and renal cell cancer. Proc Natl Acad Sci U S A 98:3387–3392

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Lister DM, Graham-Brown RA, Burns DA et al (1988) Collagenosis nuchae – a new entity? Clin Exp Dermatol 13:263–264

    Article  PubMed  CAS  Google Scholar 

  • Lund HZ (1957) Tumors of the skin. In: Atlas of tumor pathology, 1st ser., fasc. 2. Armed Forces Institute of Pathology, Washington, DC, S 274–277

    Google Scholar 

  • Markel SF, Enzinger FM (1982) Neuromuscular hamartoma – a benign „triton tumor“ composed of mature neural and striated muscle elements. Cancer 49:140–144

    Article  PubMed  CAS  Google Scholar 

  • Marshall-Taylor C, Fanburg-Smith JC (2000) Hemosiderotic fibrohistiocytic lipomatous lesion: ten cases of a previously undescribed fatty lesion of the foot/ankle. Mod Pathol 13:1192–1199

    Article  PubMed  CAS  Google Scholar 

  • Meis JM, Enzinger FM (1993) Chondroid lipoma. A unique tumor simulating liposarcoma and myxoid chondrosarcoma. Am J Surg Pathol 17:1103–1112

    Article  PubMed  CAS  Google Scholar 

  • Mills AE (1989) Rhabdomyomatous mesenchymal hamartoma of skin. Am J Dermatopathol 11:58–63

    Article  PubMed  CAS  Google Scholar 

  • Morton TG (1876) A peculiar and painful affection of the fourth metatarso-phalangeal articulation. Am J Med Sci 71:37–45

    Article  Google Scholar 

  • O’Brien JE, Stout AP (1964) Malignant fibrous xanthomas. Cancer 17:1445–1455

    Article  PubMed  Google Scholar 

  • Pulitzer DR, Reed RJ (1985) Nerve-sheath myxoma (perineurial myxoma). Am J Dermatopathol 7:409–421

    Article  PubMed  CAS  Google Scholar 

  • Rapini RP, Golitz LE (1989) Sclerotic fibromas of the skin. J Am Acad Dermatol 20:266–271

    Article  PubMed  CAS  Google Scholar 

  • Reed RJ, Fine RM, Meltzer HD (1972) Palisaded, encapsulated neuromas of the skin. Arch Dermatol 106:865–870

    Article  PubMed  CAS  Google Scholar 

  • Reed WB, Walker R, Horowitz R (1973) Cutaneous leiomyomata with uterine leiomyomata. Acta Derm Venereol 53:409–416

    PubMed  CAS  Google Scholar 

  • Regan JM, Bickle WH, Broders AC (1945) Infiltrating benign lipomas of the extremities. West J Surg 54:87

    Google Scholar 

  • Reye RD (1956) A consideration of certain subdermal fibromatous tumors of infancy. J Pathol Bacteriol 72:149–154

    Article  PubMed  CAS  Google Scholar 

  • Reye RD (1965) Recurring digital fibrous tumors of childhood. Arch Pathol 80:228–231

    PubMed  CAS  Google Scholar 

  • Rodriguez-Jurado R, Palacios C, Durán-Mc Kinster C et al. (2004) Medallion-like dermal dendrocyte hamartoma: a new clinically and histopathologically distinct lesion. J Am Acad Dermatol 51: 359–363

    Google Scholar 

  • Sahl WJ Jr (1978) Mobile encapsulated lipomas. Formerly called encapsulated angiolipomas. Arch Dermatol 114:1684–1686

    Article  PubMed  Google Scholar 

  • Schwann T (1838) Ueber die Analogie in der Structur und dem Wachstum der Thiere und Pflanzen. Neue Not Geb Nat Heil 1838:33–36

    Google Scholar 

  • Shmookler BM, Enzinger FM (1981) Pleomorphic lipoma: a benign tumor simulating liposarcoma. A clinicopathologic analysis of 48 cases. Cancer 47:126–133

    Article  PubMed  CAS  Google Scholar 

  • Shmookler BM, Enzinger FM, Weiss SW (1989) Giant cell fibroblastoma. A juvenile form of dermatofibrosarcoma protuberans. Cancer 64:2154–2161

    Article  PubMed  CAS  Google Scholar 

  • Silverman TA, Enzinger FM (1985) Fibrolipomatous hamartoma of nerve. Am J Surg Pathol 9:7–14

    Article  PubMed  CAS  Google Scholar 

  • Smith NP, Wilson Jones E (1985) Multinucleate cell angiohistiocytoma – a new entity. Br J Dermatol 113 (Suppl 29):15

    Article  Google Scholar 

  • Smolle J, Auboeck L, Gogg-Retzer I et al (1989) Multinucleate cell angiohistiocytoma: a clinicopathological, immunohistochemical and ultrastructural study. Br J Dermatol 121:113–121

    Article  PubMed  CAS  Google Scholar 

  • Stout AP (1918) Tumor of the ulnar nerve. Proc N Y Pathol Soc 18:2

    Google Scholar 

  • Stout AP (1935) The peripheral manifestations of the specific nerve sheath tumor (neurolemmoma). Am J Cancer 24:751–796

    Article  Google Scholar 

  • Stout AP (1954) Juvenile fibromatoses. Cancer 7:953–978

    Article  PubMed  CAS  Google Scholar 

  • Toker C (1972) Trabecular carcinoma of the skin. Arch Dermatol 105:107–110

    Article  PubMed  CAS  Google Scholar 

  • Vellios F, Baez J, Shumacker HB (1958) Lipoblastomatosis: a tumor of fetal fat different from hibernoma. Am J Pathol 34:1149–1159

    PubMed  PubMed Central  CAS  Google Scholar 

  • Weiss SW, Enzinger FM (1978) Malignant fibrous histiocytoma: an analysis of 200 cases. Cancer 41:2250–2266

    Article  PubMed  CAS  Google Scholar 

  • Worret WI, Burgdorf W (1978) Angeborenes plattenartiges Osteoma cutis bei einem Säugling. Hautarzt 29:590–596

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dermatohistologisches Labor und Hautarztpraxis, Nürnberg, Deutschland

    Michael Wilk

  2. Universitätsklinik für Dermatologie und Venerologie, Medizinische Universität, Innsbruck, Österreich

    Bernhard Zelger

Authors
  1. Michael Wilk
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bernhard Zelger
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Michael Wilk .

Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum München, München, Germany

    Gerd Plewig

  2. Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum München, München, Germany

    Thomas Ruzicka

  3. Klinik für Dermatologie, Venerologie und Allergologie, J.W.Goethe-Universität, Frankfurt, Germany

    Roland Kaufmann

  4. Klinik für Dermatologie und Allergologie, Universitätsklinikum Marburg, Marburg, Germany

    Michael Hertl

Section Editor information

  1. Direktor der Klinik für Dermatologie, Venerologie und Allergologie, Klinikum der J.W.Goethe-Universität, Frankfurt am Main, Deutschland

    Roland Kaufmann

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Wilk, M., Zelger, B. (2018). Mesenchymale und neuronale Tumoren. In: Plewig, G., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco’s Dermatologie, Venerologie und Allergologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49544-5_106

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-49544-5_106

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-49543-8

  • Online ISBN: 978-3-662-49544-5

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation