Zusammenfassung
Benigne exophytische, papilläre oder verruköse Läsionen des Plattenepithels der Mundhöhle, des Oropharynx und des Kehlkopfes können – mit wenigen Ausnahmen − dem Plattenepithel-Papillom (SCP), der Verruca vulgaris (VV), dem Condyloma acuminatum (CA) oder der fokalen epithelialen Hyperplasie (FEH) zugeordnet werden. Die Mehrzahl der Läsionen stellt einander ähnliche Varianten der Mukosaproliferationen dar, die häufig durch Infektionen mit dem humanen Papillom- Virus (HPV) induziert werden. Sie zeigen mehr oder weniger sich überlappende klinische und morphologische Eigenschaften, jedoch ein unterschiedliches biologisches Verhalten, das von weitgehend biologisch bedeutungslosen bis hin zu potenziell lebensbedrohenden Läsionen reicht. Eine Klassifikation dieser Veränderungen in infektiöse (VV, CA, FEH) und neoplastische (SCP) Läsionen ist schlecht fundiert. Außer der Kehlkopf- Papillomatose haben papilläre Läsionen generell einen günstigen Verlauf.
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Gale, N., Zidar, N. (2009). Benigne und potentiell maligne Läsionen des Plattenepithels und Plattenepithelkarzinom. In: Cardesa, A., Rudolph, P., Mentzel, T., Slootweg, P. (eds) Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72885-6_1
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