Pulmonary Langerhans cell histiocytosis

Case contributed by Bruno Di Muzio
Diagnosis almost certain

Presentation

Smoker.

Patient Data

Age: 50 years
Gender: Female

Multiple small thin-walled pulmonary cysts scattered within the upper lobes, right middle lobe, and superior segments of the lower lobes. There are a few scattered small solid pulmonary nodules. Biapical pleural parenchymal band of scarring. The airways are normal.  The pleural spaces are clear.

There is no lymphadenopathy.  Surgical clips in the anterior mediastinum, no discrete masses.  The imaged superior abdomen is unremarkable, a small hepatic cyst is unchanged. No suspicious osseous lesions.

Case Discussion

This patient has been followed-up in the respiratory clinics due to her pulmonary Langerhans cell histiocytosis. This is a late follow-up scan in where, different from centrilobular emphysema, the features are those of lung cysts with discrete thin walls. Although present, the nodules are not a distinct finding on this scan but were seen in her old imaging (not shown). The longterm and current smoking history with lung cysts in a predilection for the mid and upper zones make LCH the most likely diagnosis on imaging. 

 

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