Léo Apotheker (born 18 September 1953) is a German business executive. He served briefly as the chief executive officer of Hewlett-Packard from November 2010 until his dismissal in September 2011. He also served as co-chief executive officer of SAP from April 2008 until he resigned in February 2010 following a decision by that company not to renew his contract.

During his tenure as chief executive at HP, the company lost more than $30 billion in market capitalization after a series of strategic missteps by the company, leading to his resignation. At SAP, which he joined in 1988 and where he spent more than 20 years, he played an instrumental role in developing and implementing a number of significant changes. 

Apotheker currently sits on the board of KMD, Schneider Electric SA, Steria, and the non-profit organization PlaNet Finance. He previously served on the board of directors of GT Nexus. Apotheker is fluent in five languages: German, Dutch, French, English and Hebrew.