Zusammenfassung
Die Technik der Gewebekultur, die zu Beginn dieses Jahrhunderts insbesondere durch Harrison (1907, Burrows (1910), Carell (1912) und deren Mitarbeiter entwickelt wurde, eröffnete die Möglichkeit, „die Struktur und das Verhalten lebender Zellen unabhängig von den Einflüssen des Gesamtorganismus zu studieren” (Fell, 1935). Auch die Wirkung von Röngenstrahlen auf Zellen in vitro wurde schon damals untersucht. Mit nahezu unveränderter Technik wurden in den nächsten 40 Jahren vor allem zwei Probleme immer wieder aufgegriffen: zumeinen suchte man nach der,„tödlichen Dosis fürCarcinom-zellen” (Wood u. Prime, 1922), zum anderen beobachtete man die direkt unter Bestrahlung auftretenden oder unmittelbar folgenden Veränderungen in den kultivierten Zellen, insbesondere die Veränderungen der mitotischen Aktivität.
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Trott, KR. (1972). Strahlenwirkungen auf die Vermehrung von Säugetierzellen. In: Hug, O., Zuppinger, A. (eds) Strahlenbiologie / Radiation Biology. Handbuch der Medizinischen Radiologie / Encyclopedia of Medical Radiology, vol 2 / 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80710-7_2
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