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Sodium hydrosulfide (CAS 207683-19-0)

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Alternate Names:
Sodium Hydrogen Sulfide
Application:
Sodium hydrosulfide is an H2S donor
CAS Number:
207683-19-0
Purity:
≥60%
Molecular Weight:
56.06
Molecular Formula:
HS•Na
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium hydrosulfide is an important sulfur compound that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Characterized by its pungent odor, it is primarily used as a reducing agent and a sulfur source in various chemical reactions. It is highly soluble in water, forming an alkaline solution that is widely utilized in the leather industry for tanning processes. Additionally, it is employed in the production of dyes, flotation agents, and other chemicals. In scientific research, sodium hydrosulfide finds applications in studies involving sulfur chemistry, synthesis of organic compounds, and as a precursor for generating hydrogen sulfide (H2S) gas. The mechanism of action of sodium hydrosulfide primarily revolves around its ability to release hydrogen sulfide (H2S) when dissolved in water. H2S is a gas that can act as a reducing agent and participate in various chemical reactions. Sodium hydrosulfide provides a convenient and controllable source of H2S, allowing researchers to study its effects on biological systems, signaling pathways, and physiological processes. It is an H2S donor commonly used in cellular and whole animal experimental systems. Sodium hydrosulfide has also been used to suggest that H2S promotes neutrophil migration, reduces airway inflammation, and protects neurites, heart, and intestine from chemical or ischemic-reperfusion damage.

References:

  1. Differentiated astrocytes acquire sensitivity to hydrogen sulfide that is diminished by the transformation into reactive astrocytes.  |  Tsugane, M., et al. 2007. Antioxid Redox Signal. 9: 257-69. PMID: 17115938
  2. Sodium hydrosulfide alleviates pulmonary artery collagen remodeling in rats with high pulmonary blood flow.  |  Li, X., et al. 2008. Heart Vessels. 23: 409-19. PMID: 19037589
  3. Initial characterization of hydrogen sulfide effects in female sexual function.  |  Srilatha, B., et al. 2009. J Sex Med. 6: 1875-84. PMID: 19453900
  4. A general and straightforward method for the synthesis of 2-trifluoromethylbenzothiazoles.  |  Zhu, J., et al. 2010. Org Lett. 12: 2434-6. PMID: 20402511
  5. Effect of hypoxia in mice mesenteric arteries surrounded by adipose tissue.  |  Maenhaut, N. and Van de Voorde, J. 2011. Acta Physiol (Oxf). 203: 235-44. PMID: 21362151
  6. Endogenous hydrogen sulfide insufficiency as a predictor of sexual dysfunction in aging rats.  |  Srilatha, B., et al. 2012. Aging Male. 15: 153-8. PMID: 22455401
  7. Depolarizing actions of hydrogen sulfide on hypothalamic paraventricular nucleus neurons.  |  Khademullah, CS. and Ferguson, AV. 2013. PLoS One. 8: e64495. PMID: 23691233
  8. Hydrogen sulfide in posthemorrhagic shock mesenteric lymph drainage alleviates kidney injury in rats.  |  Han, B., et al. 2015. Braz J Med Biol Res. 48: 622-8. PMID: 25945746
  9. Hydrogen Sulfide Facilitates Vaginal Lubrication by Activation of Epithelial ATP-Sensitive K(+) Channels and Cystic Fibrosis Transmembrane Conductance Regulator.  |  Sun, Q., et al. 2016. J Sex Med. 13: 798-807. PMID: 27114193
  10. Cerebroprotective effects of hydrogen sulfide in homocysteine-induced neurovascular permeability: Involvement of oxidative stress, arginase, and matrix metalloproteinase-9.  |  Nath, N., et al. 2019. J Cell Physiol. 234: 3007-3019. PMID: 30206943
  11. Hepatoprotective effect of sodium hydrosulfide on hepatic encephalopathy in rats.  |  Kwon, KW., et al. 2019. Korean J Physiol Pharmacol. 23: 263-270. PMID: 31297010
  12. Hydrogen sulfide (H2S) and nitric oxide (NO) alleviate cobalt toxicity in wheat (Triticum aestivum L.) by modulating photosynthesis, chloroplastic redox and antioxidant capacity.  |  Ozfidan-Konakci, C., et al. 2020. J Hazard Mater. 388: 122061. PMID: 31954305
  13. Nanofibrous Membrane Dressings Loaded With Sodium Hydrogen Sulfide/Endothelial Progenitor Cells Promote Wound Healing.  |  Lian, J., et al. 2021. Front Bioeng Biotechnol. 9: 657549. PMID: 34422776
  14. Protective effect of H2S on LPSinduced AKI by promoting autophagy.  |  Li, T., et al. 2022. Mol Med Rep. 25: PMID: 35059738

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium hydrosulfide, 5 g

sc-229304
5 g
$46.00

Sodium hydrosulfide, 100 g

sc-229304A
100 g
$56.00

Sodium hydrosulfide, 1 kg

sc-229304B
1 kg
$85.00

Sodium hydrosulfide, 3 kg

sc-229304C
3 kg
$110.00

If its about 60% pure, what kind of impurities are contaminaiting in it? And more specifically, how much water is in it?

Asked by: Anonymous
Thank you for your question. Please contact our technical service team for a certificate of analysis of the current batch of this compound.
Answered by: Tech Support Europe
Date published: 2022-10-25

I am searching for NaHS - Sodium Hydrosulfide. Do you have any?

Asked by: Shamus001
Thank you for your question. Yes, we do offer this product, this question is on the webpage for this item. Please contact Technical Service if you have any further questions.
Answered by: Tech Service
Date published: 2019-04-09
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Rated 5 out of 5 by from Gao S; et alGao S; et al. (PubMed ID: 26423115) determined that sodium hydrosulfide stopped the down-regulation of BDNF by corticosterone, and protected PC12 cells from corticosterone-induced cytotoxicity. -SCBT Publication Review
Date published: 2015-02-06
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Sodium hydrosulfide | CAS 207683-19-0 is rated 5.0 out of 5 by 1.
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